Also See Cool Videos in 2011
And More Cool Videos.
Yale Professor Paul Bloom describes the important research on happiness in this lecture.
Another great talk by Paul Bloom (he also has a great free video lecture series on psychology)
Jason Fried makes a lot of great points on why the office is a productivity killer.
Gary Vaynerchuk on following your passion.
Scott Berkun is an excellent speaker (he also wrote Confessions of a Public Speaker)
Simon Sinek explains that people don’t buy what you do, they buy why you do it.